Oral antihistamine (pill)

Xyzal (levocetirizine): what the label says

Xyzal (levocetirizine) is a once-a-day oral antihistamine (pill) for runny nose, sneezing, itchy, watery eyes and itching of the nose or throat. May cause drowsiness. Labeled for ages 6 and up.

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Xyzal

At a glance

Genericlevocetirizine
Active ingredientLevocetirizine dihydrochloride 5 mg
TypeOral antihistamine (pill)
Label usesrunny nose, sneezing, itchy, watery eyes, itching of the nose or throat
Nasal congestion on labelNo
DrowsinessMay cause drowsiness
How oftenOnce a day, in the evening
Youngest age on label6 years
Maximum1 tablet (5 mg) in 24 hours for ages 12 to 64

What it treats

The label says Xyzal temporarily relieves these symptoms due to hay fever or other upper respiratory allergies:

  • Runny nose
  • Sneezing
  • Itchy, watery eyes
  • Itching of the nose or throat

Dose by age

WhoLabel directions
Adults and children 12 to 641 tablet (5 mg) once daily in the evening. Not more than 1 tablet in 24 hours.
Children 6 to 11Half a tablet (2.5 mg) once daily in the evening. Not more than half a tablet in 24 hours.
Adults 65 and olderAsk a doctor.
Children under 6Do not use.

Drowsiness

May cause drowsiness The label says "drowsiness may occur" and to avoid alcohol. It is taken in the evening.

Warnings on the label

  • Do not use if you have kidney disease.
  • Do not use if you have ever had an allergic reaction to this product or any of its ingredients.
  • Ask a doctor before use if you have ever had trouble urinating or emptying your bladder.
  • Alcohol, sedatives and tranquilizers may increase drowsiness.

Levocetirizine is an isomer (the active form) of cetirizine, the ingredient in Zyrtec. Ask a pharmacist before taking both.

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Frequently asked questions

Is Xyzal non-drowsy?

The label says "drowsiness may occur" and to avoid alcohol. It is taken in the evening.

How often can you take Xyzal?

Once a day, in the evening. Maximum on the label: 1 tablet (5 mg) in 24 hours for ages 12 to 64.

Can children take Xyzal?

Adults and children 12 to 64: 1 tablet (5 mg) once daily in the evening. Not more than 1 tablet in 24 hours. Children 6 to 11: Half a tablet (2.5 mg) once daily in the evening. Not more than half a tablet in 24 hours. Children under 6: Do not use.

Is generic levocetirizine the same as Xyzal?

Store-brand products list their active ingredient on the Drug Facts label. If it says Levocetirizine dihydrochloride 5 mg, it is the same medicine at the same strength. Check the label for other added ingredients.

Source

Xyzal Allergy 24HR Drug Facts label (Drugs.com, from the manufacturer's label). Labeler: Chattem, Inc.. Checked October 17, 2026. Labels change, so read the one on your box. This page summarizes the label and is not medical advice. How we check.

Pollen season

Get ready before pollen season

A reminder before tree pollen season, when allergists suggest starting medicine, plus the ragweed season heads-up in August.

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